Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group
  • Journal of Near Infrared Spectroscopy
  • Vol. 20,
  • Issue 1,
  • pp. 223-235
  • (2012)

Time-Domain Broadband near Infrared Spectroscopy of the Female Breast: A Focused Review from Basic Principles to Future Perspectives

Not Accessible

Your library or personal account may give you access

Abstract

A review of near infrared (NIR) spectroscopy of the female breast performed using time domain broadband systems is presented, summarising the key studies performed at Politecnico di Milano. The time domain approach, based on pulsed tunable lasers and single-photon detection, makes it possible to uncouple absorption from scattering contributions and to derive tissue optical properties in vivo non-invasively. The basic tissue absorbers in the 600–1100 nm range are discussed, together with the interpretation of the scattering spectra. Inter- and intra-subject variations in breast optical properties are addressed based on in vivo measurements on different women and on the same subject as a function of the menstrual cycle phase and of the measurement geometry. Results demonstrate that a specific breast type can be identified for each woman, ultimately related to the water, lipid and collagen content and to the scattering properties. As an example of the application of spectroscopy-derived information, we discuss the non-invasive optical detection of breast density as an important risk factor for breast cancer, envisaging an attractive contribution of NIR spectroscopy to the fight against breast cancer on both a medical diagnostics and research level.

© 2012 IM Publications LLP

PDF Article
More Like This
Near-infrared spectral imaging of the female breast for quantitative oximetry in optical mammography

Yang Yu, Ning Liu, Angelo Sassaroli, and Sergio Fantini
Appl. Opt. 48(10) D225-D235 (2009)

Collagen quantification in breast tissue using a 12-wavelength near infrared spectral tomography (NIRST) system

Yan Zhao, William R. Burger, Mingwei Zhou, Erica B. Bernhardt, Peter A. Kaufman, Roshani R. Patel, Christina V. Angeles, Brian W. Pogue, Keith D. Paulsen, and Shudong Jiang
Biomed. Opt. Express 8(9) 4217-4229 (2017)

Seven-wavelength time-resolved optical mammography extending beyond 1000 nm for breast collagen quantification

Paola Taroni, Antonio Pifferi, Elena Salvagnini, Lorenzo Spinelli, Alessandro Torricelli, and Rinaldo Cubeddu
Opt. Express 17(18) 15932-15946 (2009)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved